IRF AND STAT TRANSCRIPTION FACTORS - FROM BASIC BIOLOGY TO ROLES IN INFECTION, PROTECTIVE IMMUNITY, AND PRIMARY IMMUNODEFICIENCIES

IRF and STAT Transcription Factors - From Basic Biology to Roles in Infection, Protective Immunity, and Primary Immunodeficiencies

The induction and action of type I interferon (IFN) is of fundamental importance in human immune defenses toward microbial pathogens, particularly viruses.Basic discoveries within the molecular and cellular signaling pathways regulating type I IFN induction and downstream actions have shown the essential role of the IFN regulatory factor (IRF) and

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Experimental Investigation of a 300 kW Organic Rankine Cycle Unit with Radial Turbine for Low-Grade Waste Heat Recovery

The performance of a 300 kW organic Rankine cycle (ORC) prototype was experimentally investigated for low-grade waste heat recovery in industry.The prototype employed a specially developed single-stage radial turbine that was integrated with a semi-hermetic three-phase cyspera cream where to buy asynchronous generator.R245fa was selected as the wor

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What controls the coarse sediment yield to a Mediterranean delta? The case of the Llobregat River (NE Iberian Peninsula)

The human pressure upon an alluvial river in the Mediterranean region has changed its riverine and deltaic landscapes.The river has been channelized in the last 70 years while the delta has been retreating for more than a century (a set of data unknown, so far).The paper concentrates on the fluvial component, trying to connect it to the delta evolu

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